Scopolin
| Code | Size | Price |
|---|
| TAR-T3888-1mL | 1 mL * 10 mM (in DMSO) | £127.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
| TAR-T3888-20mg | 20mg | £159.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
Scopolin formation is increased by the enhanced activity of PAL. Scopolin can reduce the clinical symptoms of rat AIA by inhibiting inflammation and angiogenesis, and this compound may be a potent agent for angiogenesis related diseases and can serve as a structural base for screening more potent synthetic analogs.
CAS:
531-44-2
Formula:
C16H18O9
Molecular Weight:
354.311
Pathway:
Chromatin/Epigenetic; DNA Damage/DNA Repair
Purity:
0.9987
SMILES:
COc1cc2ccc(=O)oc2cc1O[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O
Target:
Sirtuin
References
Gao F, Robe K, Bettembourg M, et al. The Transcription Factor bHLH121 Interacts with bHLH105 (ILR3) and its Closest Homologs to Regulate Iron Homeostasis in Arabidopsis. The Plant Cell. 2020, 32(2): 508-524
Ference C M, Manthey J, Narciso J, et al. Detection of phenylpropanoids in citrus leaves produced in response to Xanthomonas citri subsp. Citri. Phytopathology. 2020, 110(2): 287-296
Pan R,et al. Scopolin isolated from Erycibe obtusifolia Benth stems suppresses adjuvant-induced rat arthritis by inhibiting inflammation and angiogenesis. Int Immunopharmacol. 2009 Jul;9(7-8):859-69.
Rollinger JM,et al. Acetylcholinesterase inhibitory activity of scopolin and scopoletin discovered by virtual screening of natural products. J Med Chem. 2004 Dec 2;47(25):6248-54.
Robe K, Conejero G, Gao F, et al. Coumarin accumulation and trafficking in Arabidopsis thaliana: a complex and dynamic process. New Phytologist. 2021 Feb;229(4):2062-2079
Robe K, Conejero G, Gao F, et al. Coumarin accumulation and trafficking in Arabidopsis thaliana: a complex and dynamic process[J]. New Phytologist. 2020
Gao F, Robe K, Bettembourg M, et al. The Transcription Factor bHLH121 Interacts with bHLH105 (ILR3) and its Closest Homologs to Regulate Iron Homeostasis in Arabidopsis[J]. The Plant Cell. 2020, 32(2): 508-524.
Ference C M, Manthey J, Narciso J, et al. Detection of phenylpropanoids in citrus leaves produced in response to Xanthomonas citri subsp. citri[J]. Phytopathology. 2020, 110(2): 287-296.