Salirasib

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TargetMol
Product Code: TAR-T6163
Supplier: TargetMol
CodeSizePrice
TAR-T6163-10mg10mg£111.00
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TAR-T6163-25mg25mg£149.00
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Quantity:
TAR-T6163-50mg50mg£201.00
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Quantity:
TAR-T6163-100mg100mg£258.00
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TAR-T6163-200mg200mg£389.00
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Quantity:
Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

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Documents

Further Information

Bioactivity:
Salirasib(Ki=2.6 μM), an effective competitive prenylated protein methyltransferase (PPMTase) inhibitor, inhibits Ras methylation with potential antineoplastic activity.
CAS:
162520-00-5
Formula:
C22H30O2S
Molecular Weight:
358.54
Pathway:
Autophagy; MAPK; GPCR/G Protein
Purity:
0.9933
SMILES:
CC(C)=CCCC(C)=CCCC(C)=CCSc1ccccc1C(O)=O
Target:
Autophagy; Ras

References

Gana-Weisz M, et al. Biochem Biophys Res Commun. 1997, 900-904. Marciano D, et al. J Med Chem. 1995, 38(8), 1267-1272. Marom M, et al. J Biol Chem. 1995, 270(38), 22263-22270. Reif S, et al. J Hepatol. 1999, 31(6),, 1053-1061. Weisz B, et al. Oncogene. 1999, 18(16), 2579-2588.