FCCP
Code | Size | Price |
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TAR-T6834-5mg | 5mg | £99.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T6834-1mL | 1 mL * 10 mM (in DMSO) | £111.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T6834-10mg | 10mg | £111.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T6834-25mg | 25mg | £144.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T6834-50mg | 50mg | £204.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T6834-100mg | 100mg | £319.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T6834-200mg | 200mg | £487.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T6834-500mg | 500mg | £736.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Images
Documents
Further Information
Bioactivity:
FCCP, a potent uncoupler of oxidative phosphorylation in mitochondria, transport protons across cell membranes leading to disrupts ATP synthesis.
CAS:
370-86-5
Formula:
C10H5F3N4O
Molecular Weight:
254.172
Pathway:
Metabolism; Membrane transporter/Ion channel
Purity:
0.995
SMILES:
FC(F)(F)Oc1ccc(NN=C(C#N)C#N)cc1
Target:
ATPase; Mitochondrial Metabolism
References
Mu?oz F, et al. FEBS Lett. 2001, 492(1-2):156-159.
Shi J, Zhang F, Chen L, et al. Systemic mitochondrial disruption is a key event in the toxicity of bacterial pore?forming toxins to Caenorhabditis elegans. Environmental Microbiology. 2021 Sep;23(9):4896-4907
Liang S, Zhu C, Suo C, et al. Mitochondrion-Localized SND1 Promotes Mitophagy and Liver Cancer Progression Through PGAM5. Frontiers in Oncology. 2022, 12: 857968-857968
Guimar?es EL, et al. BMC Gastroenterol. 2012, 12:68.
Liu H, Sun Y, Xu H, et al. PTEN-induced putative kinase 1 regulates mitochondrial quality control and is essential for the maturation of human induced pluripotent stem cell-derived cardiomyocytes. Genes & Diseases. 2022
Shi J, Zhang F, Chen L, et al. Systemic mitochondrial disruption is a key event in the toxicity of bacterial pore?forming toxins to Caenorhabditis elegans[J]. Environmental Microbiology.
Zander-Fox DL, et al. Biol Reprod. 2015, 92(5):124.