alpha-Tocopherolquinone
Code | Size | Price |
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TAR-T7050-10mg | 10mg | £95.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T7050-1mL | 1 mL * 10 mM (in DMSO) | £98.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T7050-25mg | 25mg | £122.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T7050-50mg | 50mg | £145.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Images
Documents
Further Information
Bioactivity:
During hypoxia in rats, levels of α-tocopherylquinon have been found to rise. It is reported to downregulate the respiratory activity of mitochondria. It has also displayed antioxidant activities after it is reduced to tocopherylhydroquinone.
CAS:
7559-04-8
Formula:
C29H50O3
Molecular Weight:
446.716
Pathway:
oxidation-reduction
Purity:
0.9813
SMILES:
CC(C)CCC[C@@H](C)CCC[C@@H](C)CCC[C@@](C)(O)CCC1=C(C)C(=O)C(C)=C(C)C1=O
Target:
Antioxidant
References
Lars Gille, et al. Redox-interaction of ?-tocopheryl quinone with isolated mitochondrial cytochrome complex[J]. Biochemical Pharmacology, 2004, 68(2):373-381.
Siegel D, et al. The Reduction of ?-Tocopherolquinone by Human NAD(P)H:Quinone Oxidoreductase: The Role of ?-Tocopherolhydroquinone as a Cellular Antioxidant[J]. Molecular Pharmacology, 1997, 52(2):300-305.
Kanazawa H, et al. Determination of ?-tocopherol and ?-tocopherylquinone in rat tissues and plasma by high-performance liquid chromatography with electrochemical detection.[J]. Chemical & Pharmaceutical Bulletin, 2000, 48(10):1462-1466.