[Leu5]-Enkephalin
| Code | Size | Price |
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| TAR-T7173-100mg | 100mg | Enquire | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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| TAR-T7173-50mg | 50mg | Enquire | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
[Leu5]-Enkephalin is an endogenous neuropeptide involved in nociception and an agonist of δ-opioid and μ-opioid receptors (Kis = 4.0 and 3.4 nM, respectively)
CAS:
58822-25-6
Formula:
C28H37N5O7
Molecular Weight:
555.632
Pathway:
GPCR/G Protein; Endocrinology/Hormones; Metabolism; Neuroscience
Purity:
0.98
SMILES:
CC(C)C[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)CNC(=O)[C@@H](N)Cc1ccc(O)cc1)C(O)=O
Target:
Opioid Receptor; Endogenous Metabolite
References
Fabisiak A , Ma?gorzata Soboci?ska, El?bieta Kamysz, et al. Antinociceptive potency of enkephalins and enkephalinase inhibitors in the mouse model of colorectal distension - proof of concept[J]. Chemical Biology & Drug Design, 2018, 92(1).
Meunier J C , Moisand C . Binding of leu5-enkephalin and met5-enkephalin to a particulate fraction from rat cerebrum[J]. Febs Letters, 1977, 77(2):0-213.