Homogentisic acid
Code | Size | Price |
---|
TAR-TCS2070-1mL | 1 mL * 10 mM (in DMSO) | £111.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-TCS2070-20mg | 20mg | £119.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Images
Documents
Further Information
Bioactivity:
1. Homogentisic acid shows interesting antioxidant and antiradical activities, and protective effect against thermal-cholesterol degradation, comparable to those of well known antioxidants. 2. Homogentisic acid is the primary precursor of melanin synthesis in Vibrio cholerae, a Hyphomonas strain, and Shewanella colwelliana. 3. A derivative of homogentisic acid which inhibits Pfnek-1 with an IC(5) around 1.8 muM, this product is moderately active in vitro against a FcB1 P. falciparum strain (IC(5) = 12 muM).
CAS:
451-13-8
Formula:
C8H8O4
Molecular Weight:
168.148
Pathway:
oxidation-reduction; Metabolism
Purity:
0.9988
SMILES:
OC(=O)Cc1cc(O)ccc1O
Target:
Antioxidant; Endogenous Metabolite
References
Hughes A T , Milan A M , Davison A S , et al. Serum markers in alkaptonuria: simultaneous analysis of homogentisic acid, tyrosine and nitisinone by liquid chromatography tandem mass spectrometry[J]. Annals of Clinical Biochemistry: An international journal of biochemistry and laboratory medicine, 2015:0004563215571969.