Flavokawain C
| Code | Size | Price |
|---|
| TAR-TN1645-5mg | 5mg | £1,741.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
Flavokawain C is a melanogenesis inhibitor, it inhibited melanogenesis with IC50 values of 6.9 μM. Flavokawain C has anti-tumor activity, it inhibited cell cycle and promoted apoptosis, associated with endoplasmic reticulum stress and regulation of MAPKs and Akt signaling pathways in HCT 116 human colon carcinoma cells.
CAS:
56798-34-6
Formula:
C17H16O5
Molecular Weight:
300.31
Pathway:
MAPK; Immunology/Inflammation; Neuroscience
Purity:
0.98
SMILES:
COc1cc(O)c(C(=O)C=Cc2ccc(O)cc2)c(OC)c1
Target:
NADPH-oxidase; MAPK; AChR
References
The flavokawains: uprising medicinal chalconesCancer Cell International 2013, 13:102