Irinotecan hydrochloride trihydrate
Code | Size | Price |
---|
TAR-T0486-25mg | 25mg | £101.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T0486-50mg | 50mg | £114.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T0486-1mL | 1 mL * 10 mM (in DMSO) | £116.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T0486-100mg | 100mg | £128.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Images
Documents
Further Information
Bioactivity:
Irinotecan HCl-trihydrate keeps DNA from unwinding by inhibiting topoisomerase 1.
CAS:
136572-09-3
Formula:
C33H45ClN4O9
Molecular Weight:
677.19
Pathway:
DNA Damage/DNA Repair; Autophagy
Purity:
0.9979
SMILES:
O.O.O.Cl.CCc1c2Cn3c(cc4c(COC(=O)[C@]4(O)CC)c3=O)-c2nc2ccc(OC(=O)N3CCC(CC3)N3CCCCC3)cc12
Target:
Topoisomerase; Autophagy
References
1. Pavillard V, et al. Cancer Chemother Pharmacol. 2002, 49(4), 329-335.
2. Tobin P, et al. Br J Clin Pharmacol. 2006, 62(1), 122-129.
3. Shingyoji M, et al. Cancer Sci. 2004, 95(6), 537-540.
4. van Ark-Otte J, et al. Br J Cancer. 1998, 77(12), 2171-2176.
5. Jansen WJ, et al. Int J Cancer. 1997, 70(3):335-340.