Edasalonexent
Code | Size | Price |
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TAR-T15198-5mg | 5mg | £304.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T15198-50mg | 50mg | £1,163.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T15198-100mg | 100mg | £1,564.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Images
Documents
Further Information
Bioactivity:
Edasalonexent is an orally bioavailable inhibitor of NF-κB.
CAS:
1204317-86-1
Formula:
C31H42N2O3
Molecular Weight:
490.688
Pathway:
NF-κb
Purity:
0.98
SMILES:
CCC=C/CC=C/CC=C/CC=C/CC=C/CC=C/CCC(=O)NCCNC(=O)c1ccccc1O
Target:
NF-κB
References
1. Hammers DW, et al. Disease-modifying effects of orally bioavailable NF-?B inhibitors in dystrophin-deficient muscle. JCI Insight. 2016 Dec 22;1(21):e90341.
2. Donovan JM, et al. A Novel NF-?B Inhibitor, Edasalonexent (CAT-1004), in Development as a Disease-Modifying Treatment for Patients With Duchenne Muscular Dystrophy: Phase 1 Safety, Pharmacokinetics, and Pharmacodynamics in Adult Subjects. J Clin Pharmacol. 2017 May;57(5):627-639.