Captopril disulfide
Code | Size | Price |
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TAR-T20512-25mg | 25mg | £432.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T20512-50mg | 50mg | £731.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T20512-100mg | 100mg | £1,068.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Images
Documents
Further Information
Bioactivity:
Captopril disulfide, a metabolite of Captopril, is a new antihypertensive agent.
CAS:
64806-05-9
Formula:
C18H28N2O6S2
Molecular Weight:
432.55
Purity:
0.98
SMILES:
C[C@H](CSSC[C@@H](C)C(=O)N1CCC[C@H]1C(O)=O)C(=O)N1CCC[C@H]1C(O)=O
References
1. Bojarska J, Maniukiewicz W, Fruzi?ski A, Siero? L, Remko M. Captopril and its dimer captopril disulfide: comparative structural and conformational studies. Acta Crystallogr C Struct Chem. 2015 Mar;71(Pt 3):199-203. doi: 10.1107/S2053229615002582. Epub 2015 Feb 18. PubMed PMID: 25734850.
2. Mahmoud WM, K?mmerer K. Captopril and its dimer captopril disulfide: photodegradation, aerobic biodegradation and identification of transformation products by HPLC-UV and LC-ion trap-MS(n). Chemosphere. 2012 Aug;88(10):1170-7. doi: 10.1016/j.chemosphere.2012.03.064. Epub 2012 Apr 24. PubMed PMID: 22534199.
3. Drummer OH, Jarrott B. Captopril disulfide conjugates may act as prodrugs: disposition of the disulfide dimer of captopril in the rat. Biochem Pharmacol. 1984 Nov 15;33(22):3567-71. PubMed PMID: 6095854.
4. Bathala MS, Weinstein SH, Meeker FS Jr, Singhvi SM, Migdalof BH. Quantitative determination of captopril in blood and captopril and its disulfide metabolites in plasma by gas chromatography. J Pharm Sci. 1984 Mar;73(3):340-4. PubMed PMID: 6371216.