Senazodan hydrochloride

TargetMol
Product Code: TAR-T28752
Supplier: TargetMol
CodeSizePrice
TAR-T28752-5mg5mg£270.00
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Quantity:
TAR-T28752-50mg50mg£1,026.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T28752-100mg100mg£1,589.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

Images

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Further Information

Bioactivity:
Senazodan HCl, a phosphodiesterase inhibitor, is used potentially for the treatment of heart failure.
CAS:
98326-33-1
Formula:
C15H15ClN4O
Molecular Weight:
302.76
Purity:
0.98
SMILES:
Cl.O=C1CCC(=NN1)c1ccc(Nc2ccncc2)cc1

References

1. Yang G, Liu L, Xu J, Li T. Effects of MCI-154 on vascular reactivity and its mechanisms after hemorrhagic shock in rats. J Cardiovasc Pharmacol. 2006 Jun;47(6):751-7. PubMed PMID: 16810075. 2. Yang GM, Liu LM. [Effect of MCI-154 on calcium sensitivity of vascular smooth muscle and its mechanism in hemorrhagic shock in rats]. Zhongguo Wei Zhong Bing Ji Jiu Yi Xue. 2005 Jan;17(1):7-11. Chinese. PubMed PMID: 15636703. 3. Chen HZ, Cui XL, Zhao HC, Zhao LY, Lu JY, Wu BW. Inotropic effects of MCI-154 on rat cardiac myocytes. Sheng Li Xue Bao. 2004 Jun 25;56(3):301-5. PubMed PMID: 15224141. 4. Takahashi S, Cho S, Hara T, Ureshino H, Tomiyasu S, Sumikawa K. The interaction of MCI-154, a calcium sensitizer, and isoflurane on systemic and coronary hemodynamics in chronically instrumented dogs. Anesth Analg. 2004 Jan;98(1):30-6, table of contents. PubMed PMID: 14693578.