Harmalol hydrochloride

TargetMol
Product Code: TAR-TN1724
Supplier: TargetMol
CodeSizePrice
TAR-TN1724-1mg1mg£119.00
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TAR-TN1724-5mg5mg£189.00
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Quantity:
TAR-TN1724-10mg10mg£246.00
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Quantity:
TAR-TN1724-25mg25mg£367.00
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Quantity:
TAR-TN1724-50mg50mg£507.00
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Quantity:
TAR-TN1724-100mg100mg£694.00
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Quantity:
Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

Images

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Further Information

Bioactivity:
Harmidol hydrochloride is a natural product
CAS:
6028-07-5
Formula:
C12H13ClN2O
Molecular Weight:
236.7
Pathway:
Metabolism|oxidation-reduction
Purity:
0.98
SMILES:
Cl.CC1=NCCc2c1[nH]c1cc(O)ccc21
Target:
P450|Antioxidant

References

Tarpley M, et al. Identification of harmine and ?-carboline analogs from a high-throughput screen of an approved drug collection; profiling as differential inhibitors of DYRK1A and monoamine oxidase A and for in vitro and in vivo anti-cancer studies. Eur J Pharm Sci. 2021;162:105821. Brierley DI, et al. Developments in harmine pharmacology--implications for ayahuasca use and drug-dependence treatment. Prog Neuropsychopharmacol Biol Psychiatry. 2012;39(2):263-272. Tse SY, et al. Antioxidative properties of harmane and beta-carboline alkaloids. Biochem Pharmacol. 1991;42(3):459-46 El Gendy MA, et al. Harmaline and harmalol inhibit the carcinogen-activating enzyme CYP1A1 via transcriptional and posttranslational mechanisms. Food Chem Toxicol. 2012;50(2):353-362. Han E S, et al. Inhibition of Glutamate-Induced Change in Mitochondrial Membrane Permeability in PC12 cells by 1-Methylated ?-carbolines. The Korean Society of Applied Pharmacology. 2003;11(2): 112-118.