Pyrimethamine
Code | Size | Price |
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TAR-T0849-50mg | 50mg | £101.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T0849-1mL | 1 mL * 10 mM (in DMSO) | £111.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T0849-100mg | 100mg | £112.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T0849-200mg | 200mg | £133.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Images
Documents
Further Information
Bioactivity:
Pyrimethamine is a competitive inhibitor of dihydrofolate reductase (DHFR), used as an antimalarial drug.
CAS:
58-14-0
Formula:
C12H13ClN4
Molecular Weight:
248.71
Pathway:
Metabolism; Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Microbiology/Virology
Purity:
0.9974
SMILES:
CCc1nc(N)nc(N)c1-c1ccc(Cl)cc1
Target:
DHFR; Antifolate; Parasite
References
1. Maegawa GH, et al. J Biol Chem, 2007, 282(12), 9150-9161.
2. Akao M, et al. J Am Coll Cardiol, 2002, 40(4), 803-810.
3. Ito S, et al. J Pharmacol Exp Ther, 2010, 333(1), 341-350.