NSC305787 hydrochloride
Code | Size | Price |
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TAR-T12263L-5mg | 5mg | £351.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T12263L-50mg | 50mg | £1,267.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T12263L-100mg | 100mg | £1,669.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Images
Documents
Further Information
Bioactivity:
NSC305787 hydrochloride is an inhibitor of ezrin (Kd: 5.85 μM). NSC305787 hydrochloride inhibits the phosphorylation of ezrin caused by PKC? (IC50: 8.3 μM). It has an antitumor activity.
CAS:
53868-26-1
Formula:
C25H31Cl3N2O
Molecular Weight:
481.89
Purity:
0.98
SMILES:
Cl.OC(C1CCCCN1)c1cc(nc2c(Cl)cc(Cl)cc12)C12CC3CC(CC(C3)C1)C2
References
1. Bulut G, et al. Small molecule inhibitors of ezrin inhibit the invasive phenotype of osteosarcoma cells. Oncogene. 2012 Jan 19;31(3):269-81.
2. ?elik H, et al. Ezrin Inhibition Up-regulates Stress Response Gene Expression. J Biol Chem. 2016 Jun 17;291(25):13257-70.