CCT129957
Code | Size | Price |
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TAR-T14903-100mg | 100mg | Enquire | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T14903-50mg | 50mg | Enquire | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Images
Documents
Further Information
Bioactivity:
CCT129957 is a potent phospholipase C-γ (PLC-γ) inhibitor (IC50: ~3 μM; GC50: 15 μM). It also inhibits Ca2+ release in squamous carcinoma cells at ~15 μM.
CAS:
883098-58-6
Formula:
C17H15N3O3
Molecular Weight:
309.325
Purity:
0.98
SMILES:
[O-][N+](=O)c1cccc2cc([nH]c12)C(=O)NCCc1ccccc1
References
1. Reynisson J, et al. The identification of novel PLC-gamma inhibitors using virtual high throughput screening. Bioorg Med Chem. 2009 Apr 15;17(8):3169-76.
2. Feng L, et al. The effect of PLC-?2 inhibitors on the growth of human tumour cells. Eur J Med Chem. 2012 Aug;54:463-9.