MB05032
Code | Size | Price |
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TAR-T16020-50mg | 50mg | £711.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T16020-100mg | 100mg | £1,187.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Images
Documents
Further Information
Bioactivity:
MB05032 targeted the AMP binding site of fructose 1,6-bisphosphatase (FBPase), which is a special and efficacious inhibitor of GNG.
CAS:
261365-11-1
Formula:
C11H15N2O4PS
Molecular Weight:
302.28
Purity:
0.98
SMILES:
CC(C)Cc1sc(N)nc1-c1ccc(o1)P(O)(O)=O
References
1. Erion MD, et al. MB06322 (CS-917): A potent and selective inhibitor of fructose 1,6-bisphosphatase for controlling gluconeogenesis in type 2 diabetes. Proc Natl Acad Sci U S A. 2005 May 31;102(22):7970-5.
2. Zhang Y, et al. Fructose-1,6-bisphosphatase regulates glucose-stimulated insulin secretion of mouse pancreatic beta-cells. Endocrinology. 2010 Oct;151(10):4688-95.