Dicoumarol
| Code | Size | Price |
|---|
| TAR-T0809-500mg | 500mg | £103.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
Dicumarol is a hydroxycoumarin originally isolated from molding sweet-clover hay, with anticoagulant and vitamin K depletion activities. Dicumarol is a competitive inhibitor of vitamin K epoxidereductase; thus, it inhibits vitamin K recycling and causes depletion of active vitamin K in blood. This prevents the formation of the active form of prothrombin and several other coagulant enzymes, and inhibits blood clotting.
CAS:
66-76-2
Formula:
C19H12O6
Molecular Weight:
336.299
Pathway:
Metabolism; PI3K/Akt/mTOR signaling
Purity:
0.999
SMILES:
Oc1c(Cc2c(O)c3ccccc3oc2=O)c(=O)oc2ccccc12
Target:
Dehydrogenase; NADPH; PDK
References
1. Jaiswal AK. Arch Biochem Biophys. 2000, 375(1):62-8.