Acemetacin
| Code | Size | Price |
|---|
| TAR-T1467-200mg | 200mg | £94.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
| TAR-T1467-1mL | 1 mL * 10 mM (in DMSO) | £107.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
Acemetacin is a carboxymethyl ester of indometacin. It is a potent non-steroidal anti-inflammatory drug, derived from the indol-3-acetic acid, whose activity is thought to be mainly through its active metabolite indomethacin. In clinical trials, acemetacin exhibits a better gastric tolerability compared to its active metabolite indometacin.
CAS:
53164-05-9
Formula:
C21H18ClNO6
Molecular Weight:
415.83
Pathway:
Immunology/Inflammation; Neuroscience
Purity:
0.9926
SMILES:
COc1ccc2n(C(=O)c3ccc(Cl)cc3)c(C)c(CC(=O)OCC(O)=O)c2c1
Target:
COX
References
1. Tavares IA, et al. Int J Tissue React, 1993, 15(2), 49-53.
2. Ch?vez-Pi?a AE, et al. Br J Pharmacol. 2007 Nov;152(6):930-8.
3. Gil-Flores M, et al. Methods Find Exp Clin Pharmacol. 2010 Mar;32(2):101-5.
4. Wada Y, et al. Jpn J Pharmacol, 1984 , 34(4), 468-470.
5. Gil-Flores M, et al. Methods Find Exp Clin Pharmacol, 2010, 32(2), 101-105.