Fmoc-8-amino-3,6-dioxaoctanoic acid
Code | Size | Price |
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TAR-T15304-1g | 1g | £96.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
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Further Information
Bioactivity:
Fmoc-8-amino-3,6-dioxaoctanoic acid is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). It is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
CAS:
166108-71-0
Formula:
C21H23NO6
Molecular Weight:
385.416
Pathway:
PROTAC
Purity:
0.9961
SMILES:
OC(=O)COCCOCCNC(=O)OCC1c2ccccc2-c2ccccc12
Target:
PROTAC Linker
References
1. Nakamura A, et al. Chemogenetic Control of Protein Anchoring to Endomembranes in Living Cells with Lipid-Tethered Small Molecules. Biochemistry. 2020 Jan 21;59(2):205-211.