JNJ-46778212
Code | Size | Price |
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TAR-T15619-100mg | 100mg | Enquire | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T15619-50mg | 50mg | Enquire | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Images
Documents
Further Information
Bioactivity:
JNJ-46778212 is an effective mGlu5 allosteric modulator (EC50: 260 nM).
CAS:
1363281-27-9
Formula:
C20H17FN2O3
Molecular Weight:
352.365
Pathway:
Neuroscience
Purity:
0.98
SMILES:
Fc1ccc(cc1)C(=O)N1CCc2nc(COc3ccccc3)oc2C1
Target:
GluR
References
1. Conde-Ceide S, et al. Discovery of VU0409551/JNJ-46778212: An mGlu5 Positive Allosteric Modulator Clinical Candidate Targeting Schizophrenia. ACS Med Chem Lett. 2015 May 20;6(6):716-20.