Esculetin

TargetMol
Product Code: TAR-T2798
Supplier: TargetMol
CodeSizePrice
TAR-T2798-100mg100mg£107.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T2798-1mL1 mL * 10 mM (in DMSO)£111.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

Images

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Further Information

Bioactivity:
Esculetin is a coumarin derivative from various natural plant products with various biological and pharmaceutical properties including anti-edema, anti-inflammatory and anti-tumour effects. It inhibits lipoxygenases (LOs).
CAS:
305-01-1
Formula:
C9H6O4
Molecular Weight:
178.143
Pathway:
PI3K/Akt/mTOR signaling; Cytoskeletal Signaling; Metabolism
Purity:
0.9976
SMILES:
Oc1cc2ccc(=O)oc2cc1O
Target:
Lipoxygenase; Akt; PI3K

References

1. Yang JY, et al. Obesity (Silver Spring). 2006, 14(10):1691-9. 2. Park SS, et al. Oncol Rep. 2011, 25(1):223-30. 3. Wang J, et al. Braz J Med Biol Res. 2015, 48(3):245-53. 4. A. Witaicenis, et al. European Journal of Inflammation. 2013, 11(2):433-446. 5. Jang S A, Hwang Y H, Kim T, et al. Anti-Osteoporotic and Anti-Adipogenic Effects of the Water Extract of Drynaria roosii Nakaike in Ovariectomized Mice Fed a High-Fat Diet[J]. Molecules. 2019, 24(17): 3051.