3-Hydroxyphenylacetic acid

TargetMol
Product Code: TAR-T4829
Supplier: TargetMol
CodeSizePrice
TAR-T4829-100mg100mg£104.00
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Quantity:
TAR-T4829-1mL1 mL * 10 mM (in DMSO)£107.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
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Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

Images

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Further Information

Bioactivity:
3-Hydroxyphenylacetic acid is a rutin metabolite and an antioxidant. It has a protective biological activity in human. It is a substrate of enzyme 4-hydroxyphenylacetate 3-monooxygenase [EC 1.14.13.3] in the pathway tyrosine metabolism. 3-Hydroxyphenylacetic acid is found to be associated with phenylketonuria, which is an inborn error of metabolism.
CAS:
621-37-4
Formula:
C8H8O3
Molecular Weight:
152.149
Pathway:
; Metabolism
Purity:
0.9821
SMILES:
OC(=O)Cc1cccc(O)c1
Target:
Endogenous Metabolite

References

Young S N , Davis B A , Gauthier S . Precursors and metabolites of phenylethylamine, m and p-tyramine and tryptamine in human lumbar and cisternal cerebrospinal fluid.[J]. Journal of Neurology Neurosurgery & Psychiatry, 1982, 45(7):633-9. Baba S , Furuta T , Horie M , et al. Studies on drug metabolism by use of isotopes XXVI: Determination of urinary metabolites of rutin in humans[J]. Journal of Pharmaceutical Sciences, 2010, 70(7):780-782. Nahmias C , Wahl L M , Amano S , et al. Chirakal R. Equilibration of 6-[18F]fluoro-L-m-tyrosine between plasma and erythrocytes[J]. Journal of Nuclear Medicine Official Publication Society of Nuclear Medicine, 2000, 41(10):1636. Davis B A , Boulton A A . Longitudinal urinary excretion of some "trace" acids in a human male[J]. Journal of Chromatography, 1981, 222(2):161-169. Davis B A , Durden D A , Boulton A A . Plasma concentrations of p- and m-hydroxyphenylacetic acid and phenylacetic acid in humans: gas chromatographic--high-resolution mass spectrometric analysis.[J]. J Chromatogr, 1982, 230(2):219-230.