7-Dehydrocholesterol
| Code | Size | Price |
|---|
| TAR-T4923-1mL | 1 mL * 10 mM (in DMSO) | £111.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
| TAR-T4923-100mg | 100mg | £111.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
7-Dehydrocholesterol down-regulates cholesterol biosynthesis in cultured Smith-Lemi-Opitz syndrome skin fibroblasts.
CAS:
434-16-2
Formula:
C27H44O
Molecular Weight:
384.648
Pathway:
Metabolism
Purity:
0.9967
SMILES:
CC(C)CCC[C@@H](C)[C@H]1CC[C@H]2C3=CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C
Target:
Endogenous Metabolite
References
Muzzin K B, Harper L F. Smith-Lemli-Opitz syndrome: a review, case report and dental implications[J]. Special Care in Dentistry, 2010, 23(1):22-27.
Ho C , Fung C , Siu T , et al. Lathosterolosis: A Disorder Of Cholesterol Biosynthesis Resembling Smith-lemli-opitz Syndrome[J]. Jimd Rep, 2013, 12:129-134.
Johnson D W, ten Brink H J, Jakobs C. A rapid screening procedure for cholesterol and dehydrocholesterol by electrospray ionization tandem mass spectrometry[J]. Journal of Lipid Research, 2001, 42(10):1699-705.
Sethi J K, Vidalpuig A J. Thematic review series: adipocyte biology. Adipose tissue function and plasticity orchestrate nutritional adaptation.[J]. Journal of Lipid Research, 2007, 48(6):1253-1262.
Lehmann B , Genehr T , Knuschke P , et al. UVB-Induced Conversion of 7-Dehydrocholesterol to 1?,25-Dihydroxyvitamin D3 in an In Vitro Human Skin Equivalent Model[J]. Journal of Investigative Dermatology, 2001, 117(5):1179.