(S)-2-Hydroxy-3-phenylpropanoic acid

TargetMol
Product Code: TAR-T5290
Supplier: TargetMol
CodeSizePrice
TAR-T5290-100mg100mg£104.00
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Quantity:
TAR-T5290-1mL1 mL * 10 mM (in DMSO)£107.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
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Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

Images

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Further Information

Bioactivity:
L-3-Phenyllactic acid (or PLA) is a chiral aromatic compound involved in phenylalanine metabolism. It is likely produced from phenylpyruvate via the action of lactate dehydrogenase. The D-form of this organic acid is typically derived from bacterial sources while the L-form is almost certainly endogenous. Levels of phenyllactate are normally very low in blood or urine. High levels of PLA in the urine or blood are often indicative of phenylketonuria (PKU) and hyperphenylalaninemia (HPA). PKU is due to lack of the enzyme phenylalanine hydroxylase (PAH) so that phenylalanine is converted not to tyrosine but to phenylpyruvic acid (a precursor of phenylacetate).
CAS:
20312-36-1
Formula:
C9H10O3
Molecular Weight:
166.176
Pathway:
; Metabolism
Purity:
0.9963
SMILES:
O[C@@H](Cc1ccccc1)C(O)=O
Target:
Endogenous Metabolite

References

Tekewe A, et al. Development and validation of HPLC method for the resolution of drug intermediates: DL-3-Phenyllactic acid, DL-O-acetyl-3-phenyllactic acid and (+/-)-mexiletine acetamide enantiomers. Talanta. 2008 Mar 15;75(1):239-45.