20-(tert-Butoxy)-20-oxoicosanoic acid
Code | Size | Price |
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TAR-T9785-500mg | 500mg | £111.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
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Further Information
Bioactivity:
20-(tert-Butoxy)-20-oxoicosanoic acid is a alkyl-chain-based PROTAC linker. 20-(tert-Butoxy)-20-oxoicosanoic acid is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
CAS:
683239-16-9
Formula:
C24H46O4
Molecular Weight:
398.628
Pathway:
PROTAC
Purity:
0.98
SMILES:
CC(C)(C)OC(=O)CCCCCCCCCCCCCCCCCCC(O)=O
Target:
PROTAC Linker
References
Nalawansha DA, et al. PROTACs: An Emerging Therapeutic Modality in Precision Medicine. Cell Chem Biol. 2020;27(8):998-985.
Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017;16(5):315-337.