5-Aminosalicylic Acid
| Code | Size | Price |
|---|
| TAR-T0646-500mg | 500mg | £107.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
Mesalamine is an anti-inflammatory agent, structurally related to the SALICYLATES, which is active in INFLAMMATORY BOWEL DISEASE. It is considered to be the active moiety of SULPHASALAZINE.
CAS:
89-57-6
Formula:
C7H7NO3
Molecular Weight:
153.137
Pathway:
Neuroscience; Metabolism; DNA Damage/DNA Repair; Cytoskeletal Signaling; Immunology/Inflammation; NF-κb
Purity:
0.9788
SMILES:
Nc1ccc(O)c(c1)C(O)=O
Target:
NF-κB; Lipoxygenase; COX; Glutathione Peroxidase; Endogenous Metabolite; PAK; PPAR
References
1. Egan LJ, et al. J Biol Chem,1999, 274(37), 26448-26453.
2. Khare V, et al. Biochem Pharmacol,2013, 85(2), 234-244.
3. Das KK, et al. Mol Pharmacol,2009, 76(1), 183-191.
4. Khare V, et al. Biochem Pharmacol,2014, 87(2), 312-320.
5. Graham PM, et al. Mol Cell Biochem,2013, 378(1-2), 291-298.
6. Dammann K, et al. PAK1 modulates a PPAR?/NF-?B cascade in intestinal inflammation. Biochim Biophys Acta. 2015 Oct;1853(10 Pt A):2349-60.