Acridone
| Code | Size | Price |
|---|
| TAR-T20003-1mL | 1 mL * 10 mM (in DMSO) | £94.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
| TAR-T20003-1g | 1g | £95.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
Acridone is an organic compound based on the acridine skeleton. Acridone could induce cell apoptosis, inhibited ABCG2 (ATP-binding cassette sub-family G member 2) protein, and adjusted hormone level.
CAS:
578-95-0
Formula:
C21H13NO
Molecular Weight:
295.341
Pathway:
Microbiology/Virology; Membrane transporter/Ion channel
Purity:
0.9957
SMILES:
O=c1c2c(ccc3ccccc23)[nH]c2ccc3ccccc3c12
Target:
Antibacterial; ABC
References
1. Xia YF, Chu HJ, Kuang GF, Jiang GJ, Che YC. Inhibition effects of acridone on the growth of breast cancer cells in vivo. Eur Rev Med Pharmacol Sci. 2018 Apr;22(8):2356-2363. doi: 10.26355/eurrev_201804_14827. PubMed PMID: 29762857.
2. Piboonprai K, Khumkhrong P, Khongkow M, Yata T, Ruangrungsi N, Chansriniyom C, Iempridee T. Anticancer activity of arborinine from Glycosmis parva leaf extract in human cervical cancer cells. Biochem Biophys Res Commun. 2018 Jun 12;500(4):866-872. doi: 10.1016/j.bbrc.2018.04.175. Epub 2018 May 1. PubMed PMID: 29705700.
3. Posri P, Suthiwong J, Takomthong P, Wongsa C, Chuenban C, Boonyarat C, Yenjai C. A new flavonoid from the leaves of Atalantia monophylla (L.) DC. Nat Prod Res. 2018 Mar 30:1-7. doi: 10.1080/14786419.2018.1457667. [Epub ahead of print] PubMed PMID: 29600742.
4. Ulicna K, Bednarikova Z, Hsu WT, Holztragerova M, Wu JW, Hamulakova S, Wang SS, Gazova Z. Lysozyme amyloid fibrillization in presence of tacrine/acridone-coumarin heterodimers. Colloids Surf B Biointerfaces. 2018 Jun 1;166:108-118. doi: 10.1016/j.colsurfb.2018.03.010. Epub 2018 Mar 9. PubMed PMID: 29550545.