Hetacillin
| Code | Size | Price |
|---|
| TAR-T32064-500mg | 500mg | £370.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
Hetacillin is a β-lactam antibiotic that belongs to the amino-penicillin family and is converted to ampicillin by esterase. It is a prodrug that has no antimicrobial activity of its own, but it rapidly breaks down acetone in the human body to form ampicillin, which is active against a variety of bacteria.
CAS:
3511-16-8
Formula:
C19H23N3O4S
Molecular Weight:
389.47
Purity:
0.98
SMILES:
CC1(C)SC2C(N3C(=O)C(NC3(C)C)c3ccccc3)C(=O)N2C1C(O)=O
References
1. Lindquist DA, Baynes RE, Smith GW. Short communication: Pharmacokinetics of intramammary hetacillin in dairy cattle milked 3 times per day. J Dairy Sci. 2015 Mar;98(3):1856-61. doi: 10.3168/jds.2014-8715. Epub 2014 Dec 26. PubMed PMID: 25547305.
2. Galanopoulou P, Karageorgiou C, Dimakopoulou K. Effect of enzyme induction on bioavailability of hetacillin in patients treated with anticonvulsants and chlorpromazine. Eur J Drug Metab Pharmacokinet. 1990 Jan-Mar;15(1):15-8. PubMed PMID: 2384113.
3. Gubert S, Palacin C, Sacrist?n A, Ortiz JA. Synthesis and oral absorption of hetacillin and hetamoxicillin labile esters. Chem Pharm Bull (Tokyo). 1987 Jun;35(6):2366-72. PubMed PMID: 3664833.
4. Couvaris M, Galanopoulou P, Karageorgiou C, Jalil HA, Varonos D. Bioavailability of hetacillin in rats after liver enzyme induction by various inducers with or without protein binding properties. Eur J Drug Metab Pharmacokinet. 1985 Jan-Mar;10(1):27-32. PubMed PMID: 4029217.