Proxyphylline
| Code | Size | Price |
|---|
| TAR-T5940-500mg | 500mg | £103.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
| TAR-T5940-1mL | 1 mL * 10 mM (in DMSO) | £107.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
Proxyphylline is a dual of adenosine A1/A2a receptor inhibitor and phosphodiesterase (PDE) inhibitor. Proxyphylline acts as a cardiac stimulant, vasodilator and bronchodilator.
CAS:
603-00-9
Formula:
C10H14N4O3
Molecular Weight:
238.247
Pathway:
GPCR/G Protein; Metabolism; Neuroscience
Purity:
0.9979
SMILES:
CC(O)Cn1cnc2n(C)c(=O)n(C)c(=O)c12
Target:
PDE; Adenosine Receptor
References
Kukovetz W R , G P?ch, Holzmann S . Overadditive synergism between theophylline, diprophylline and proxyphylline in tracheal smooth muscle relaxation[J]. Arzneimittel-Forschung, 1983, 33(10):1450-1454.
Rasmussen F V , Waldorff S , Madsen L . Pharmacokinetics and bronchodilatory effect of proxyphylline and theophylline.[J]. Eur J Respir Dis, 1984, 65(1):20-27.
Takeda K , Katano Y , Nakagawa Y , et al. EFFECTS OF AMINOPHYLLINE, PROXYPHYLLINE AND A PROXYPHYLLINE-MELILOTUS EXTRACT-RUTIN MIXTURE (THEOESBERIVEN) ON THE HEART AND THE CORONARY CIRCULATION[J]. The Japanese Journal of Pharmacology, 1977, 27(5):709-720.