Hydrocortisone
Code | Size | Price |
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TAR-T1614-500mg | 500mg | £107.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T1614-1mL | 1 mL * 10 mM (in DMSO) | £111.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Images
Documents
Further Information
Bioactivity:
Hydrocortisone, a glucocorticoid receptor agonist, promotes protein catabolism, gluconeogenesis, capillary wall stability, renal excretion of calcium, and suppresses immune and inflammatory responses. Therapeutic Hydrocortisone is a synthetic or semisynthetic analog of natural hydrocortisone hormone produced by the adrenal glands with primary glucocorticoid and minor mineralocorticoid effects.
CAS:
50-23-7
Formula:
C21H30O5
Molecular Weight:
362.466
Pathway:
Metabolism; Endocrinology/Hormones
Purity:
0.9995
SMILES:
C[C@]12C[C@H](O)[C@H]3[C@@H](CCC4=CC(=O)CC[C@]34C)[C@@H]1CC[C@]2(O)C(=O)CO
Target:
Glucocorticoid Receptor; Endogenous Metabolite
References
1. F?rster C, et al. J Physiol. 2008 Apr 1;586(7):1937-49.
2. Bellinghausen I, et al. J Allergy Clin Immunol, 2001, 108(2), 242-249.
3. Chappell D, et al. Basic Res Cardiol, 2009, 104(1), 78-89.
4. Chappell D, et al. Anesthesiology, 2007, 107(5), 776-784.
5. Jabara HH, et al. J Immunol, 1993, 151(9), 4528-4533.