Lansoprazole sulfide
Code | Size | Price |
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TAR-T21128-1g | 1g | £319.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
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Further Information
Bioactivity:
Lansoprazole sulfide is an impurity of Lansoprazole, which is a gastric pump inhibitor.
CAS:
103577-40-8
Formula:
C16H14F3N3OS
Molecular Weight:
353.36
Purity:
0.98
SMILES:
Cc1c(OCC(F)(F)F)ccnc1CSc1nc2ccccc2[nH]1
References
1. Mdanda S, Baijnath S, Shobo A, Singh SD, Maguire GEM, Kruger HG, Arvidsson PI, Naicker T, Govender T. Lansoprazole-sulfide, pharmacokinetics of this promising anti-tuberculous agent. Biomed Chromatogr. 2017 Dec;31(12). doi: 10.1002/bmc.4035. Epub 2017 Jul 13. PubMed PMID: 28623874.
2. Rybniker J, Vocat A, Sala C, Busso P, Pojer F, Benjak A, Cole ST. Lansoprazole is an antituberculous prodrug targeting cytochrome bc1. Nat Commun. 2015 Jul 9;6:7659. doi: 10.1038/ncomms8659. PubMed PMID: 26158909; PubMed Central PMCID: PMC4510652.
3. Pearce RE, Rodrigues AD, Goldstein JA, Parkinson A. Identification of the human P450 enzymes involved in lansoprazole metabolism. J Pharmacol Exp Ther. 1996 May;277(2):805-16. PubMed PMID: 8627562.
4. Landes BD, Petite JP, Flouvat B. Clinical pharmacokinetics of lansoprazole. Clin Pharmacokinet. 1995 Jun;28(6):458-70. Review. PubMed PMID: 7656504.