5-Hydroxymethyluracil
Code | Size | Price |
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TAR-T5255-1g | 1g | £109.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
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Further Information
Bioactivity:
5-Hydroxymethyluracil is an oxidation damage product derived from thymine or 5-methylcytosine. It is a product of thymine dioxygenase. Additional deamination products such as 5-hydroxymethyluracil are formed when cells are under oxidative stress that is induced either by oxidizing agents or by mitochondrial dysfunction.
CAS:
4433-40-3
Formula:
C5H6N2O3
Molecular Weight:
142.114
Pathway:
Metabolism;
Purity:
0.9776
SMILES:
OCc1c[nH]c(=O)[nH]c1=O
Target:
Endogenous Metabolite
References
Kow YW. Repair of deaminated bases in DNA. Free Radic Biol Med. 2002 Oct 1;33(7):886-93.