Apocynin

TargetMol
Product Code: TAR-T6391
Supplier: TargetMol
CodeSizePrice
TAR-T6391-1mL1 mL * 10 mM (in DMSO)£111.00
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Quantity:
TAR-T6391-1g1g£111.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
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Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

Images

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Further Information

Bioactivity:
Apocynin is a specific NADPH-oxidase inhibitor (IC50: 10 μM).
CAS:
498-02-2
Formula:
C9H10O3
Molecular Weight:
166.176
Pathway:
Autophagy; Apoptosis; Metabolism
Purity:
0.9998
SMILES:
COc1cc(ccc1O)C(C)=O
Target:
Apoptosis; NADPH; Autophagy

References

Simons JM, et al. Free Radic Biol Med, 1990, 8(3), 251-258. Impellizzeri D, et al. Biochem Pharmacol, 2011, 81(5), 636-648. Deng Z, Shi F, Zhou Z, et al. M1 macrophage mediated increased reactive oxygen species (ROS) influence wound healing via the MAPK signaling in vitro and in vivo. Toxicology and Applied Pharmacology. 2019, 366: 83-95 Stefanska J, et al. Mediators Inflamm, 2008, 106507. Stolk J,et al. Am J Respir Cell Mol Biol, 1994, 11(1), 95-102. Deng Zheng, Fei Shi, Zheng Zhou, Feng Sun, Menghao Sun, Qian Sun, Lei Chen et al. M1 macrophage mediated increased reactive oxygen species (ROS) influence wound healing via the MAPK signaling in vitro and in vivo [J]. Toxicology and Applied Pharmacology. 2019 Mar 1;366:83-95. Impellizzeri D, et al. Free Radic Res, 2011, 45(2), 221-236.