Peripheral Blood CD4+ Cells
| Code | Size | Price |
|---|
| PB04015C | 15 Million Cells | £1,225.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Human
Regulatory Status: RUO
Target Species: Human
Applications:
- Autoimmune Diseases
- Biomarker Discovery
- Cell & Gene Therapy
- Regenerative Medicine Research
- Toxicology Screening
- iPSC development
Shipping:
Frozen - Dry Ice
Storage:
Frozen - Liquid Nitrogen
Further Information
Anticoagulant:
ACD-A
Cell and Tissue Source:
Peripheral Blood
Description:
Human CD4+ helper T cells express the CD4 co-receptor and play an important role in the adaptive immune system by assisting other white blood cells. These cells are activated when they are presented an antigen on the MHC class II molecule of an antigen-presenting cell (APC). Once activated, CD4+ helper T cells secrete lymphokines that assist in the activation of B cells to secrete antibodies that target specific microbes and assist in the activation of cytotoxic T cells to destroy infected target cells.
Human peripheral blood CD4+ helper T cells are enriched by means of negative selection. Cells expressing CD8, CD14, CD15, CD16, CD19, CD36, CD56, CD123, TCR?/?, and CD235a are depleted from the peripheral blood mononuclear cell population using immunomagnetic particles leaving purified, untouched CD4+ helper T cells. Cell isolations are characterized by flow cytometry to ensure a highly pure and viable cell population.
Cells were obtained using Institutional Review Board (IRB) approved consent forms and protocols.
Disease State:
Healthy
Donor Attributes:
HIV-, HepB-, HepC-
Positive, Negative or Cultured?:
Negative