Bacoside A
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TAR-T3426-1mg | 1mg | Enquire | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20°C
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Further Information
Bioactivity:
Bacoside A has a possible anticancer activity that could be inducing cell cycle arrest and apoptosis through Notch pathway in GBM in vitro. It exerts cytoprotective efficacy by attenuation of ROS generated through oxidative stress by an increase in the concentration of antioxidant enzymes and sustain membrane integrity which leads to restoring the damage caused by tBHP. Bacoside A can able to inhibit the progression of Experimental Autoimmune Encephalomyelitis (EAE) may be by the inhibition of inflammatory cytokines and chemokine evolved during active EAE. Bacoside A also has vasorelaxation.
CAS:
11028-00-5
Formula:
C41H68O13
Molecular Weight:
768.98
Pathway:
Others|Immunology/Inflammation|GPCR/G Protein|Neuroscience|Proteases/Proteasome|Apoptosis
Purity:
0.98
Target:
NOS|Dopamine Receptor|Others|TNF|ROS|MMP
References
Sebastian Aguiar and Thomas Borowski. Rejuvenation Research. 2013, 16(4): 313-326.
Thomas RB, et al. Cell Mol Neurobiol. 2013 Nov;33(8):1065-74.