BE1218

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TargetMol
Product Code: TAR-T63896
Supplier: TargetMol
CodeSizePrice
TAR-T63896-1mg1mg£108.00
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TAR-T63896-5mg5mg£148.00
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TAR-T63896-1mL1 mL * 10 mM (in DMSO)£179.00
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TAR-T63896-10mg10mg£195.00
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Quantity:
TAR-T63896-25mg25mg£289.00
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TAR-T63896-50mg50mg£389.00
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TAR-T63896-100mg100mg£538.00
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Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20°C

Images

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Documents

Further Information

Bioactivity:
BE1218 is a liver X receptor (LXR) inverse agonist active on LXRα and LXRβ with an IC50 of 9 nM and 7 nM, respectively.
CAS:
2893967-40-1
Molecular Weight:
551.69
Pathway:
Metabolism
Purity:
0.997
SMILES:
O=S(=O)(C=1C(=CC(=CC1C)C)C)N(CC2=CC=C(C=C2)C=3C=CC=C(C3)S(=O)(=O)C)CC=4C=CC=CC4F
Target:
Liver X Receptor

References

Elgendy B, et al. Synthesis and structure activity relationship of the first class of LXR inverse agonists. Bioorg Chem. 2022 ; 119:105540.