Eg5-IN-1

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TargetMol
Product Code: TAR-T77586
Supplier: TargetMol
CodeSizePrice
TAR-T77586-1mg1mg£227.00
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Quantity:
TAR-T77586-5mg5mg£458.00
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Quantity:
TAR-T77586-10mg10mg£626.00
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Quantity:
TAR-T77586-25mg25mg£938.00
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Quantity:
TAR-T77586-50mg50mg£1,267.00
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Quantity:
TAR-T77586-100mg100mg£1,653.00
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Quantity:
TAR-T77586-500mg500mg£3,227.00
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Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20°C

Images

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Documents

Further Information

Bioactivity:
Eg5-IN-1 is a potent inhibitor of the kinesin family of motor proteins (Eg5) with an IC50 value of 1.97 uM for Eg5.Eg5-IN-1 can be used in cancer research.
Molecular Weight:
418.85
Pathway:
Cytoskeletal Signaling
Purity:
0.98
SMILES:
O=C(N/N=C/C1=CC=C(F)C=C1)C(C=C2)=CC=C2NC3=CC=NC4=CC(Cl)=CC=C43
Target:
Kinesin

References

Ranade SD, et, al. Design, synthesis, molecular dynamics simulation, MM/GBSA studies and kinesin spindle protein inhibitory evaluation of some 4-aminoquinoline hybrids. Comput Biol Chem. 2023 Aug;105:107881