5α-Hydroxycostic acid
Code | Size | Price |
---|
TAR-TN3139-1mg | 1mg | £201.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-TN3139-5mg | 5mg | £463.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20°C
Images
Documents
Further Information
Bioactivity:
5alpha-Hydroxycostic acid possesses anti-angiogenic ability by interfering the VEGF- and Ang2-related pathways, and it may be a good drug candidate.
CAS:
132185-83-2
Formula:
C15H22O3
Molecular Weight:
250.33
Pathway:
Angiogenesis|Tyrosine Kinase/Adaptors|Immunology/Inflammation|Metabolism|MAPK|PI3K/Akt/mTOR signaling|Cytoskeletal Signaling
Purity:
0.98
SMILES:
C[C@]12CCCC(=C)[C@@]1(O)C[C@@H](CC2)C(=C)C(O)=O
Target:
Phospholipase|ERK|NOS|Akt|FAK|Src
References
Lei W, Xu H, Yao H, et al.5?-Hydroxycostic acid inhibits choroidal neovascularization in rats through a dual signalling pathway mediated by VEGF and angiopoietin 2.Molecular Medicine.2023, 29(1): 1-13.