Lucidone
| Code | Size | Price |
|---|
| TAR-T20980-5mg | 5mg | £1,266.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20°C
Documents
Further Information
Bioactivity:
Lucidone is a natural product with anti-inflammatory activity from Lindera erythrocarpa.
CAS:
19956-53-7
Formula:
C15H12O4
Molecular Weight:
256.26
Purity:
0.98
SMILES:
O=C1/C(C(C(OC)=C1)=O)=C(O)\C=C\C2=CC=CC=C2
References
Hsieh YH, Wang SY. Lucidone from Lindera erythrocarpa Makino fruits suppresses adipogenesis in 3T3-L1 cells and attenuates obesity and consequent metabolic disorders in high-fat diet C57BL/6 mice. Phytomedicine. 2013 Mar 15;20(5):394-400. doi: 10.1016/j.phymed.2012.11.007. Epub 2012 Dec 21. PubMed PMID: 23265843.
Senthil Kumar KJ, Liao JW, Xiao JH, Gokila Vani M, Wang SY. Hepatoprotective effect of lucidone against alcohol-induced oxidative stress in human hepatic HepG2 cells through the up-regulation of HO-1/Nrf-2 antioxidant genes. Toxicol In Vitro. 2012 Aug;26(5):700-8. doi: 10.1016/j.tiv.2012.03.012. Epub 2012 Mar 30. PubMed PMID: 22484158.
Chen WC, Wang SY, Chiu CC, Tseng CK, Lin CK, Wang HC, Lee JC. Lucidone suppresses hepatitis C virus replication by Nrf2-mediated heme oxygenase-1 induction. Antimicrob Agents Chemother. 2013 Mar;57(3):1180-91. doi: 10.1128/AAC.02053-12. Epub 2012 Dec 17. PubMed PMID: 23254429; PubMed Central PMCID: PMC3591928.
Kumar KJ, Yang HL, Tsai YC, Hung PC, Chang SH, Lo HW, Shen PC, Chen SC, Wang HM, Wang SY, Chou CW, Hseu YC. Lucidone protects human skin keratinocytes against free radical-induced oxidative damage and inflammation through the up-regulation of HO-1/Nrf2 antioxidant genes and down-regulation of NF-?B signaling pathway. Food Chem Toxicol. 2013 Sep;59:55-66. doi: 10.1016/j.fct.2013.04.055. Epub 2013 May 24. PubMed PMID: 23712098.