JS25
Code | Size | Price |
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TAR-T69646-5mg | 5mg | £930.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T69646-50mg | 50mg | £1,821.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T69646-100mg | 100mg | £2,319.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20°C
Images
Documents
Further Information
Bioactivity:
JS25 is a selective and covalent inhibitor of BTK that inactivates BTK with an IC 50 value of 5.8 nM by chelating Tyr551. JS25 inhibits cancer cells proliferation, pronounces cell death, and promotes murine xenograft model of Burkitt?s lymphoma. JS25 effectively crosses the blood-brain barrier .
CAS:
2411771-95-2
Formula:
C29H24N4O4S
Molecular Weight:
524.59
Purity:
0.98
SMILES:
O=C(C=C)NC=1C=C(C=C(C1)C)N2C(=O)C=CC=3C=NC=4C=C(C=CC4C32)C=5C=CC(=CC5)NS(=O)(=O)C