Dehydroglyasperin C
| Code | Size | Price |
|---|
| TAR-TN3806-5mg | 5mg | £770.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
| TAR-TN3806-1mL | 1 mL * 10 mM (in DMSO) | £1,247.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20°C
Documents
Further Information
Bioactivity:
Dehydroglyasperin C is a potent NAD(P)H:oxidoquinone reductase (NQO1) and phase 2 enzyme inducer. Dehydroglyasperin C possesses potent antioxidant, cancer chemopreventive, and neuroprotective activities, it has protective effects against chronic diseases caused by reactive oxygen species as well as potential as an antioxidant food additive. Dehydroglyasperin C protects neuronal cells against glutamate-induced oxidative injury through the induction of HO-1 expression, which is, in turn, activated maybe through Nrf2-Keap1 and PI3K/AKT signaling pathways.
CAS:
199331-35-6
Formula:
C21H22O5
Molecular Weight:
354.4
Pathway:
Cell Cycle/Checkpoint|MAPK|Metabolism|Neuroscience|Autophagy|Cytoskeletal Signaling|Apoptosis|Immunology/Inflammation|NF-κb|PI3K/Akt/mTOR signaling|DNA Damage/DNA Repair
Purity:
0.98
SMILES:
COc1c(C\C=C(/C)C)c(O)cc2OCC(=Cc12)c1ccc(O)cc1O
Target:
JNK|PI3K|TNF|Autophagy|NF-κB|IκB/IKK|p38 MAPK|Akt|Nrf2|NADPH|COX|ERK|DNA/RNA Synthesis