MK-0159
Code | Size | Price |
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TAR-T61933-100mg | 100mg | Enquire | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T61933-50mg | 50mg | Enquire | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20°C
Images
Documents
Further Information
Bioactivity:
MK-0159 (compound 37) is a CD38 inhibitor with oral activity and selectivity. MK-0159 can inhibit CD38 in humans, mice and rats, with IC50 of 22, 3 and 70 nM respectively. MK-0159 showed good stability in human and rodent liver microsomes. MK-0159 can increase heart and whole blood NAD+(nicotinamide adenine dinucleotide) and reduce ADPR (adenosine diphosphate ribose).
CAS:
2641484-61-7
Molecular Weight:
400.5
Purity:
0.98
SMILES:
COCCO[C@H]1CC[C@@H](CC1)NC(=O)c1cc(nc2[nH]ccc12)-c1cncs1