KS100
Code | Size | Price |
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TAR-T63992-100mg | 100mg | Enquire | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T63992-50mg | 50mg | Enquire | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20°C
Images
Documents
Further Information
Bioactivity:
KS100 is a potent inhibitor of ALDH, acting on ALDH1A1 (IC50: 334 nM), ALDH2 (IC50: 2137 nM) and ALDH3A1 (IC50: 360 nM). KS100 significantly increases ROS activity, lipid peroxidation and the accumulation of toxic aldehydes, and has low toxic anti-proliferative and anti-cancer activities. KS100 blocks the cell cycle in G2/M phase and induces apoptosis.
CAS:
2408477-54-1
Molecular Weight:
564.09
Purity:
0.98
SMILES:
Br.NC(=N)SCc1ccc(CN2C(=O)C(=O)c3cc(Br)cc(Br)c23)cc1