Hesperidin methylchalcone
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| TAR-T7980-50mg | 50mg | Enquire | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20°C
Documents
Further Information
Bioactivity:
Hesperidin methylchalcone is the Citrus original products with powerful antioxidant activity. It can suppresse experimental gout arthritis in mice by inhibiting NF-κB activation.
CAS:
24292-52-2
Formula:
C29H36O15
Molecular Weight:
624.6
Pathway:
NF-κb
Purity:
0.98
SMILES:
C[C@@H]([C@@H]([C@H]([C@H]1O)O)O)O[C@H]1OC[C@H]([C@H]([C@@H]([C@H]1O)O)O)O[C@H]1Oc1cc(OC)c(C(/C=C/c(cc2)cc(O)c2OC)=O)c(O)c1
Target:
NF-κB
References
Ruiz-Miyazawa K W , Almeida P R F , Borghi S M , et al. Hesperidin methylchalcone suppresses experimental gout arthritis in mice by inhibiting NF-kB activation[J]. Journal of Agricultural & Food Chemistry, 2018:acs.jafc.8b00959-.
Chanal J L , Cousse H , Sicart M T , et al. Absorption and elimination of (14C) hesperidin methylchalcone in the rat[J]. european journal of drug metabolism & pharmacokinetics, 1981, 6(3):171.