E3 ligase Ligand 18
Code | Size | Price |
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TAR-T17876-100mg | 100mg | Enquire | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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Quantity:
TAR-T17876-500mg | 500mg | Enquire | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
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Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20°C
Images
Documents
Further Information
Bioactivity:
E3 ligase Ligand 18 is a ligand that binds to E3 ubiquitin ligase, and it can be chemically attached to a protein ligand through a linker to create PROTACs. The resulting PROTACs function as inducers of ubiquitination-mediated degradation, targeting cancer-promoting proteins[1].
CAS:
2241669-88-3
Molecular Weight:
436.87
Purity:
0.98
SMILES:
C(N1C2=C(N=C1SC[C@H](NC(C)=O)C(O)=O)C(=O)N=C(N)N2)C3=CC=C(Cl)C=C3
References
Heterocyclic compound. WO2018143403A1.