m-PEG3-Sulfone-PEG4-propargyl
Code | Size | Price |
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TAR-T18189-100mg | 100mg | Enquire | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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TAR-T18189-500mg | 500mg | Enquire | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20°C
Images
Documents
Further Information
Bioactivity:
m-PEG3-Sulfone-PEG4-propargyl is a polyethylene glycol (PEG)-based prodrug-induced degradation (PROTAC) linker. It is utilized in the efficient synthesis of PROTACs, a class of heterobifunctional molecules designed to selectively target and degrade specific protein targets[1].
CAS:
2055041-02-4
Molecular Weight:
426.52
Purity:
0.98
SMILES:
O=S(=O)(CCOCCOCCOC)CCOCCOCCOCCOCC#C
References
An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562