PROTAC MDM2 Degrader-4
Code | Size | Price |
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TAR-T18634-100mg | 100mg | Enquire | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T18634-500mg | 500mg | Enquire | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20°C
Images
Documents
Further Information
Bioactivity:
PROTAC MDM2 Degrader-4 is a compound designed using PROTAC technology to degrade MDM2. It combines a powerful MDM2 inhibitor, a linker, and the MDM2 ligand for E3 ubiquitin ligase[1].
CAS:
2249750-24-9
Molecular Weight:
1393.19
Purity:
0.98
SMILES:
C(=O)(N1[C@@]([C@@](N=C1C2=C(OC(C)C)C=C(OC)C=C2)(C3=CC=C(Cl)C=C3)[H])(C4=CC=C(Cl)C=C4)[H])N5CC(=O)N(CC(OCCOCCOCCOC(CN6C(=O)CN(C(=O)N7[C@@]([C@@](N=C7C8=C(OC(C)C)C=C(OC)C=C8)(C9=CC=C(Cl)C=C9)[H])(C%10=CC=C(Cl)C=C%10)[H])CC6)=O)=O)CC5
References
Method of inducing of self-degradation of MDM2 using E3 ubiquitin ligase dimer amide small molecule PROTACs. CN108610333A.