Hyodeoxycholic acid sodium salt
| Code | Size | Price |
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| TAR-T2968L-100mg | 100mg | Enquire | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
| TAR-T2968L-500mg | 500mg | Enquire | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20°C
Documents
Further Information
Bioactivity:
Hyodeoxycholic acid sodium salt is a natural secondary bile acid. It improves high-density lipoprotein function, reduces farnesoid X receptor antagonist bile acids, and induces strong cytotoxicity, apoptosis, and IL-8 synthesis.
CAS:
10421-49-5
Molecular Weight:
415.56
Purity:
0.98
SMILES:
C[C@@]12[C@@]3([C@]([C@]4([C@](C)(CC3)[C@@]([C@@H](CCC(O)=O)C)(CC4)[H])[H])(C[C@H](O)[C@@]1(C[C@H](O)CC2)[H])[H])[H].[Na]
References
Fu ZD, Klaassen CD. Increased bile acids in enterohepatic circulation by short-term calorie restriction in male mice. Toxicol Appl Pharmacol. 2013 Dec 15;273(3):680-90. doi: 10.1016/j.taap.2013.10.020. Epub 2013 Oct 29. PubMed PMID: 24183703; PubMed Central PMCID: PMC4132937.
Zhang Y, Csanaky IL, Selwyn FP, Lehman-McKeeman LD, Klaassen CD. Organic anion-transporting polypeptide 1a4 (Oatp1a4) is important for secondary bile acid metabolism. Biochem Pharmacol. 2013 Aug 1;86(3):437-45. doi: 10.1016/j.bcp.2013.05.020. Epub 2013 Jun 6. PubMed PMID: 23747753; PubMed Central PMCID: PMC3774164.
Peng LQ, Cao J, Du LJ, Zhang QD, Xu JJ, Chen YB, Shi YT, Li RR. Rapid ultrasonic and microwave-assisted micellar extraction of zingiberone, shogaol and gingerols from gingers using biosurfactants. J Chromatogr A. 2017 Sep 15;1515:37-44. doi: 10.1016/j.chroma.2017.07.092. Epub 2017 Aug 1. PubMed PMID: 28789800.
Zhao DS, Jiang LL, Fan YX, Dong LC, Ma J, Dong X, Xu XJ, Li P, Li HJ. Identification of urine tauro-?-muricholic acid as a promising biomarker in Polygoni Multiflori Radix-induced hepatotoxicity by targeted metabolomics of bile acids. Food Chem Toxicol. 2017 Oct;108(Pt B):532-542. doi: 10.1016/j.fct.2017.02.030. Epub 2017 Feb 24. PubMed PMID: 28237774.