AI 77B
| Code | Size | Price |
|---|
| TAR-T29775-100mg | 100mg | Enquire | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
| TAR-T29775-500mg | 500mg | Enquire | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20°C
Documents
Further Information
Bioactivity:
AI 77B is a pseudopeptide microbial agent with gastroprotective action.
CAS:
77674-99-8
Formula:
C20H28N2O8
Molecular Weight:
424.44
Purity:
0.98
SMILES:
O=C1C=2C(C[C@@]([C@@H](NC([C@H]([C@H]([C@H](CC(O)=O)N)O)O)=O)CC(C)C)(O1)[H])=CC=CC2O
References
Urushidani T, Kasuya Y, Yano S. Ulcerogenic and antiulcerogenic effects of a new antiinflammatory drug, the gamma-lactone-N-ethyl derivative of 6-[1S-(3S,4-dihydro-8-hydroxy-1H-2-benzo- pyran-1-one-3-yl)-3-methylbutylamino]-4S,5S-dihydroxy-6-oxo-3S- ammoniohexanoate, on gastrointestinal tract in rats. Arzneimittelforschung. 1986 Sep;36(9):1383-90. PubMed PMID: 3790191.
Shimojima Y, Hayashi H. 1H-2-benzopyran-1-one derivatives, microbial products with pharmacological activity. Relationship between structure and activity in 6-[[1(S)-(3(S),4- dihydro-8-hydroxy-1-oxo-1H-2-benzopyran-3-yl)-3-methylbutyl]-amino]-4(S), 5(S)-dihydroxy-6-oxo-3(S)-ammoniohexanoate. J Med Chem. 1983 Oct;26(10):1370-4. PubMed PMID: 6620300.
Shimojima Y, Shirai T, Baba T, Hayashi H. 1H-2-Benzopyran-1-one derivatives, microbial products with pharmacological activity. Conversion into orally active derivatives with antiinflammatory and antiulcer activities. J Med Chem. 1985 Jan;28(1):3-9. PubMed PMID: 3965711.
Ghosh AK, Bischoff A, Cappiello J. Stereoselective synthesis of pseudopeptide microbial agent AI-77-B. Org Lett. 2001 Aug 23;3(17):2677-80. PubMed PMID: 11506607.