Aldoifosfamide
| Code | Size | Price |
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| TAR-T29851-100mg | 100mg | Enquire | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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| TAR-T29851-500mg | 500mg | Enquire | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20°C
Documents
Further Information
Bioactivity:
Aldoifosfamide is a metabolite of ifosfamide. Ifosfamide (also marketed as Mitoxana and Ifex) is a nitrogen mustard alkylating agent used in the treatment of cancer. It is sometimes abbreviated 'IFO''.
CAS:
120144-70-9
Molecular Weight:
277.08
Purity:
0.98
SMILES:
O=CCCOP(=O)(NCCCl)NCCCl
References
Voelcker G. Influence of the alkylating function of aldoifosfamide on the antitumor activity. Anticancer Drugs. 2017 Oct 3. doi: 10.1097/CAD.0000000000000569. [Epub ahead of print] PubMed PMID: 28984684.
Ludeman SM, Shulman-Roskes EM, Wong KK, Han SY, Anderson LW, Strong JM, Colvin OM. Oxime derivatives of the intermediary oncostatic metabolites of cyclophosphamide and ifosfamide: synthesis and deuterium labeling for applications to metabolite quantification. J Pharm Sci. 1995 Apr;84(4):393-8. PubMed PMID: 7629726.
Masurel D, Houghton PJ, Young CL, Wainer IW. Efficacy, toxicity, pharmacokinetics, and in vitro metabolism of the enantiomers of ifosfamide in mice. Cancer Res. 1990 Jan 15;50(2):252-5. PubMed PMID: 2295063.